In recent years, the revolutionary field of immunotherapy has drastically reshaped the landscape of cancer treatment, pushing the boundaries of what modern medicine can achieve. Among these advancements, Chimeric Antigen Receptor (CAR) T-cell therapy stands out as one of the most promising strategies that could redefine the future of cancer eradication. Building upon decades of immunological research, this innovative therapy harnesses the very cells of the immune system to specifically target and eliminate malignant cells, offering new hope to patients with otherwise refractory cancers.

Bloated, overpaid, outpaced by AI, and under fire from the Trump administration—big consulting firms confront a future they can’t outsource.

Point Topic tracks changes in the 4G LTE / LTE Advanced and 5G tariffs provided by mobile operators across Europe. This report presents the latest tariff benchmarks as of the end of December 2024. The data is collated within Point Topic’s Mobile Broadband Tariffs dataset.

L’avis consultatif de la cour est à la hauteur des enjeux. Il dresse un cadre juridique robuste, articulé autour du droit international coutumier, des droits humains, du droit de la mer et de plusieurs traités clés, dont la Convention-cadre des Nations Unies sur les changements climatiques de 1992, le Protocole de Kyoto de 1997 et l’Accord de Paris de 2015.

Among the key findings, the report concludes that carbon dioxide (CO2) -induced warming appears to be less damaging economically than commonly believed, and that aggressive mitigation strategies could be more harmful than beneficial. Additionally, the report finds that U.S. policy actions are expected to have undetectably small direct impacts on the global climate and any effects will emerge only with long delays. 

Climate experts say it will hobble the country's efforts to rein in rising temperatures and lessen the impacts, such as more intense storms, droughts and wildfires. The federal government's own research shows climate-fueled extreme weather is already causing $150 billion in losses a year in the US.

Unilever, Coca-Cola, Nestlé, PepsiCo, and other big names have signed an open letter calling for a ‘robust’ and ‘ambitious’ plastic pollution treaty to be finalized at INC-5.2. As members of the Business Coalition for a Global Plastics Treaty, over 290 businesses, financial institutions, and NGOs state in the letter that they consider harmonized regulations the “most effective way to pursue a lasting impact on plastic pollution while delivering economic, environmental and social value” at a national and global level.

Patients with type 2 diabetes initiated with metformin monotherapy had longer survival than did matched, non-diabetic controls. Those treated with sulphonylurea had markedly reduced survival compared with both matched controls and those receiving metformin monotherapy. This supports the position of metformin as first-line therapy and implies that metformin may confer benefit in non-diabetes. Sulphonylurea remains a concern.

Shipments have propelled Ireland, a country of 5.4 million, to the second-largest goods-trade imbalance with the U.S., behind China.

The World Health Organization estimates that more than 118 million blood donations are collected each year—with 40 percent coming from high-income countries, home to 16 percent of the world's population. This means a large portion of the global population has limited access to blood transfusion treatment. Universal artificial blood could reduce preventable deaths in injury, surgery and childbirth—settings where supply mismatches or stockouts cost millions of lives annually in low-income nations alone.

Et si le fromage pouvait s’emballer lui-même ? C’est l’idée un peu folle – mais bien réelle – imaginée par Nestlé en collaboration avec l’agence Ogilvy Colombia. Baptisé Self-Packing Cheese, ce projet expérimental transforme un sous-produit laitier souvent jeté, le petit-lait, en un emballage biodégradable capable de protéger… du fromage.

DOGE n'aura pas fait long feu. Elon Musk, en pleine tempête médiatique, s’apprête à refermer sa parenthèse politique. Son passage au sein du Department of Government Efficiency devait incarner le renouveau administratif américain. Il n’aura laissé qu’un goût amer, à l’image d’un projet sans cap et sans résultat. Pendant ce temps, Tesla, son empire technologique, vacille dangereusement.

La Chine, en pleine expansion technologique, surprend le monde avec son projet de centre de recherche sur la fusion par laser. Ce développement, révélé par des images satellites, suscite de nombreuses discussions et réflexions sur ses implications possibles. En dépassant la taille du National Ignition Facility (NIF) en Californie, cette initiative pourrait non seulement transformer le paysage scientifique, mais également influencer les dynamiques géopolitiques internationales. Les ambitions de la Chine dans ce domaine ne se limitent pas à la recherche énergétique mais s’étendent également à des applications militaires potentielles, accentuant l’intérêt et l’inquiétude à l’échelle mondiale.

Teamwork is a constant in organizational life. You will work on teams for the majority of your career. Some of those teams will be an uplifting, engaging experience—but most will be an average or even a draining experience. Because most teams aren’t high-performing ones. Most teams fail to achieve a level of performance above the average of each individual’s capabilities. Most teams lack what Stephen Covey would call “synergy” but what organizational psychologists call “collective intelligence.”

Alright, let’s dive deep into the fascinating case of the Kawasaki Corleo, a hydrogen-powered four-legged robot, and dissect it through the lens of human-centered change and innovation. As our founder Braden Kelley would tell you, it’s not simply a matter of “yes” or “no.” Innovation is a complex beast, and we must approach it with nuance.

One of the most annoying things I hear from leaders is that “we had a great strategy, but just couldn’t execute it.” That’s simply not possible. If you can’t execute it, it’s not a great strategy. Most likely, it was a fantasy cooked up by some combination of consultants and investment bankers which was enshrined in PowerPoint.

In today’s competitive landscape, a strong value proposition is essential for any business to thrive. It’s the foundation of your marketing strategy, the core of your brand promise and the key to attracting and retaining customers. But what are the ingredients of a truly successful value proposition?

A great product alone isn’t enough to stay ahead in today’s market. Businesses need to find new ways to generate revenue and build stronger customer relationships. One of the best ways to do this is by offering services—either alongside or instead of physical products. Done right, service monetization creates steady income, enhances customer loyalty, and opens new growth opportunities. Yet, many companies struggle to make it work. So why are services such a valuable revenue stream? And what are the common mistakes businesses make?

Et si manger sans mettre son jeu en pause devenait enfin possible ? C’est le pari (aussi fou que génial) relevé par la marque indonésienne Haraku Ramen Halal en dévoilant « The One Noodle », une nouille de 3,5 mètres de long pensée pour les gamers. L’idée : permettre aux joueuses et joueurs de savourer leur repas sans jamais quitter leur écran. Une création à la croisée de la food culture et du gaming, aussi inattendue qu’ultra ciblée.

Quand un restaurant irlandais décide de servir l’addition à la sauce Ryanair, même le PDG de la compagnie aérienne ne peut que sourire. De passage au restaurant Luvida à Navan, en Irlande, Michael O’Leary a eu droit à une addition personnalisée, truffée de clins d’œil aux fameuses “options payantes” qui ont fait la réputation de Ryanair. Une opération aussi culottée qu’hilarante, qui fait le tour des réseaux sociaux.