We demonstrate ultraflexible micro-endovascular (MEV) probes that can be precisely delivered through the blood vessels in the neck into sub-100-micrometer scale vessels in rat brains (Fig. 1AOpens in image viewer). In vivo electrophysiology recording of local field potentials and single-unit spikes has been selectively achieved in the cortex and olfactory bulb. The flexible probe/vessel wall/brain interface exhibits minimal inflammatory response and long-term stability.

Bloomberg announced that Neuralink will be raising its next round at a valuation of $8.5B. Nice work DJ Seo and team! For those of you wondering what this means for the larger BCI industry, I have created a thoughtful infographic.

If finalized, the round would bring Neuralink’s post-money valuation to around $9 billion, marking a significant leap from its $3.5 billion valuation in November 2023, based on PitchBook data. Discussions with potential investors are still ongoing, and terms could shift, insiders caution.

The open blast rat model used focuses on direct blast effects and injuries of the brain. The blast would result in a short standing energy wave that progressed with very high energy through the whole brain, resulting in direct lesions and spalling and shearing effects. Blast loads create very brief acceleration durations that may cause distinct neurophysiological outcomes. We used our existing patented PEG-HCCs with antioxidant properties to treat oxidative stress caused by TBI [22]. Previous studies have indicated that PEG-HCCs can recover and maintain the brain’s structural and homeostatic environment by reducing neuronal and glial cell death. In this study, we found PEG-HCCs to significantly ameliorate neuronal loss in the brain cortex, the dentate gyrus, and hippocampus and to improve blood–brain barrier integrity.

The merger brings together Neurolutions’ BCI technology and Kandu Health’s telehealth services to try to improve stroke patients’ outcomes after they leave hospital.

They keep trying to make neural interfaces happen, and I'm sceptical about 90% of the venture; as far as big tech is concerned, there's a 'closed' sign on my grey matter, thanks. Still, the other 10% of brain-computer interface projects present genuine medical advancements worth getting excited about.

In 2034, the first person landed on Mars. While she didn’t go there physically, she still experienced the planet intimately. She explored an ancient river delta and built a base. She put up a flag (China’s) and conducted a detailed analysis of rock samples. She achieved all this by inhabiting a robot via a sophisticated brain-computer interface. Some people claimed the woman had – in a real sense – been to Mars.

In a world where wearable tech is tracking every heartbeat and step, a new tool is redefining how we interact with our biology. Meet the PiEEGKit – a compact, open-source bioscience lab you can carry in your backpack. Designed for students, researchers, tech enthusiasts, and curious minds alike, this innovative device puts brain and body signals into your hands—literally.

While hippocampus represents spatial information through place cells for body navigation, whether motor areas employ a similar framework to guide hand reaching remains unknown. Here, we investigate tuning properties in dorsal premotor cortex (PMd) during naturalistic reach-and-grasp tasks in four monkeys. We find that 22% (132/601) of PMd neurons increase firing rates when the monkey’s hand occupies specific positions in space, forming the position fields. These cells represent the hand position highly efficiently, achieving ~80% accuracy for decoding hand trajectories with only 50 most dedicated position tuned cells ( ~ 10% of all recorded neurons).

Much of the recent progress has been based on advances in our ability to map the brain, identifying the various regions and their activities. A range of technologies can produce insightful images of the brain (including functional magnetic resonance imaging (fMRI) and positron emission tomography (PET)), while others monitor certain kinds of activity (including electroencephalography (EEG) and the more invasive electrocortigraphy (ECoG)).

The Georgia Tech blog also mentions that this tiny new sensor uses conductive polymer microneedles to capture electrical signals and conveys those signals along flexible polyimide/copper wires. In addition to this naturally flexible construction the implant device is less than a square millimeter.

The US Food and Drug Administration (FDA) has granted 510(k) clearance to the Layer 7 Cortical Interface — a high-resolution cortical electrode array for use in recording, monitoring, and stimulating electrical activity on the surface of the brain.

The study investigates complications associated with deep brain stimulation (DBS) surgery, analyzing patient demographics, surgical techniques, and outcomes. It identifies factors influencing complications such as pneumocephalus, infection, and hemorrhage, aiming to improve patient selection and surgical strategies for better outcomes.

The company has partnered with Nvidia to develop “cognitive AI,” which it says will allow people with severe physical disabilities to have more natural interactions with the world around them.

BCIs can’t solve AI alignment. The problem isn’t bandwidth. it’s behavioral control. AI is on an exponential compute trajectory, while human cognition—no matter how enhanced—remains biologically constrained. Even with BCIs, we would still think at a snail’s pace compared to AGI (and ASI??). AI safety depends on governance & oversight, not plugging into our brains. Alignment must be addressed in a paradigm where humans will never fully comprehend every model output or decision. This represents the grand challenge of our time, yet it is not one that BCIs will fix.

Robeauté, the medtech startup developing neurosurgical microrobots, is announcing it has raised 28 million USD led by Plural, Cherry Ventures and Kindred Ventures. Other investors including LocalGlobe, Think.Health and previous investors APEX Ventures participated, along with strategic investment from Brainlab. The new funding will be used to continue developing the technology, starting human trials in 2026 and setting up US operations ahead of FDA approval and full go-to-market.

To bridge the gap between invasive and non-invasive technologies, nanoscale materials, such as biocompatible nanoparticles, provide a promising alternative, allowing us to design materials at the scale of cellular systems and structures.

The brain-computer interface solution of brain science is based on the technical path of vascular scaffold electrodes, with unique design ideas and mature process levels, compared with similar products, showing lower electrode impedance, making stimulation more efficient and energy-saving. At the same time, the electrode has a lower cost advantage and is suitable for commercial mass production.

For implantable electronics, one of the primary goals of applying a coating barrier is to mitigate moisture-induced failures (e.g., corrosion hydration/oxidation, or shunt leakage paths) by delaying moisture permeation. For short-term applications (1–3 months), if cost is not of concern, using the hybrid layer over a single Parylene C layer could increase device reliability, especially if the moisture-sensitivity level of the electronic components is unknown. However, when designing systems for long-term applications (>1 year), a low WVTR is essential to delay moisture-induced failures.

For years now, brain-computer interfaces (BCI) have incrementally advanced, giving people with spinal injuries or lost limbs the ability to control prosthetics and computer cursors using their signals. But even though the tech has made strides, the replicating subtle, delicate, nuanced sensations of touch has remained just out of reach. Now, however, a team of researchers from the Cortical Bionics Research Group believe they have made a major breakthrough. A pair of patients wearing a BCI was able to control a bionic arm and “feel” tactile edges, shapes, and curvatures along its fingers.